I have a couple of MX 60s, is that what you are talking about? The fans are supposed to come on when the internal temp's in the controller reach whatever level. In my house, which is off-grid and 2 miles from the nearest neighbor and a mile from the nearest traveled road, things are very quiet. A friend who waxes poetic at times has described it as "seamless quiet." So we are especially aware of any "noise."
So, yes, when those fans come on, I can hear them a couple rooms away. However, they sound normal to me and I suspect that in a "usual" house with numerous noises they would be only a very minor addition to the soundscape, if that's a word.
The sound we get is simply a "fan blowing air" sound typical to something like a computer power supply fan if a bit louder than that. If you are hearing something other than that, I think you have a defective fan or one that is failing. There have been failures of these fans as I've read about on various forums. If it is a normal fan sound, it is normal. In my experience....